科研情況
1,、Hedgehog/Gli1信號通路調(diào)控STMN1表達(dá)在胃癌EMT轉(zhuǎn)化和侵襲轉(zhuǎn)移過程中的作用及機(jī)制研究,國家自然科學(xué)基金課題,,第二完成人,。
2、胃癌預(yù)警早診,、療效和預(yù)后判斷標(biāo)志物的臨床驗證,,重大慢性非傳染性疾病防控研究項目消化道腫瘤診療生物標(biāo)志物驗證及應(yīng)用研究,第四完成人,。
3,、RNF180啟動子CpG島甲基化調(diào)控胃癌淋巴結(jié)轉(zhuǎn)移機(jī)制研究,天津市應(yīng)用基礎(chǔ)與前沿技術(shù)研究計劃一般項目,,第四完成人,。
獲獎情況
1、“胃癌淋巴結(jié)轉(zhuǎn)移分期更新對患者預(yù)后評估的意義”獲2015年中國抗癌協(xié)會科技進(jìn)步三等獎,,第四完成人,。
2、“淋巴結(jié)轉(zhuǎn)移分期的改良方式對胃癌患者根治術(shù)后預(yù)后評估的臨床研究”獲2012年天津市科技進(jìn)步三等獎,,第四完成人,。
論文著作
1.張李,潘源,,梁寒等,,全胃切除術(shù)后兩種消化道重建術(shù)式的前瞻性臨床研究階段報告。中華胃腸外科雜志,,2013(12),,32-36.
2.張李,蔡明志,,鄧靖宇等,,胃腸間質(zhì)瘤156例臨床分析。中華胃腸外科雜志,,2014(17),,36-39.
3.張李,梁寒等,,ADAMTS9在腫瘤中的研究進(jìn)展,。世界最新醫(yī)學(xué)信息文摘 20(78):36-38.
4.Gang Ma, Yi Sun, Feng lin Cai, Mengmeng zhang, Han Liang,Jingyu Deng,,Rupeng Zhang,,Li Zhang. Exp Cell Res.2023;427(1).
5.Li Zhang, Han Liang. Comparison of laparoscopic and open resection for gastric gastrointestinal stromal tumors. Cancer and Surgery,2020,,1(1):8-17.ISCI
6. Liu JY, Deng JY, Zhang NN, Liu HF, Sun WL, He WT, Zhang L, Liang H. Clinical significance of the skip lymph node metastasis in pN1 stage gastric cancer patients after curative surgery. Gastroenterol Rep 2019;7(3)193-198.(IF=2.96)
7.Hou Y, Deng J, Zhang L, Xie X, Guo X, Sun C, Zhang R, Liang H. Lower expression of PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1) association with poor prognosis of gastric cancer. Int J Clin Exp Med 2015;8(11):20481-20489. (IF=0.166)
8.Deng J, Zhang R, Wu LL, Zhang L, Wang X, Liu Y, Hao X, Liang H. Superiority of the ratio between negative and positive lymph nodes for predicting the prognosis for patients with gastric cancer. Ann Surg Oncol 2015;22(4):1258-1266. ( IF=4.061)
9. Deng J, Cui J, Jiang N, Zhang R, Zhang L, Hao X, LiangH. STAT3 regulation the expression of VEGF-D in HGC-27 gastric cancer cell. Am J Transl Res 2014;6(6):756-767. (IF=3.375)
10.Deng J, Zhang R, Zhang L, Liu Y, Hao X, Liang H. Negative Node Count Improvement Prognostic Prediction of the Seventh Edition of the TNM Classification for Gastric Cancer. PLoS One 2013;8(11):e80082. (IF=2.74)
11.Deng J, Liang H, Zhang R, Sun D, Pan Y, Liu Y, Zhang L, Hao X. STAT3 is associated with lymph node metastasis in gastric cancer. Tumor Biol 2013;34(5):2791-2800.
12.Deng J, Liang H, Zhang R, Sun D, Pan Y, Zhang L, Hao X. Clinicopathologic characteristics and outcomes of surgery of middle-third gastric cancer. Tumour Biol 2012;33(6):2091-2098.
13. Deng J, Liang H, Zhang R, Sun D, Pan Y, Zhang L, Hao X. Clinicopathologic characteristics and outcomes of surgery of middle-third gastric cancer. Tumour Biol 2012;33(6):2091-2098. |